Tuesday, April 16, 2013

Viagra Resistance/Viagra Tolerance: It's a Real Thing!

As I said in an earlier post, the wonder drug Cialis quit working for me a couple of years ago, so I went back on Viagra (the 100 mg tablet, this time), and it worked GREAT, although it didn't give you that 36 hours of readiness that Cialis did.  Well, now the effectiveness of my beloved blue diamonds has begun to decrease, so that I can no longer achieve a strong enough erection for sex even though Little Willie does get somewhat expanded.  The urologist suggested a penis ring, but that only helped a little bit.  If you google "Viagra resistance" you'll find an herbal remedy sales website that cites an issue of the International Journal of  Impotence Research which details a study that suggests the efficacy of Viagra and other PDE5 inhibitors decreases over time, requiring stronger doses.  I'm here to tell ya, though, that after awhile even higher doses don't work. I wasn't able to find the actual IPIR article....But I went so far as to take two 100mg Viagras at once, with not much real effect. So, my only other options are 1) a penis pump/penis ring combo, which sounds like a lot of work for dubious reward if you ask me (if you have one of those things and are happy with it, just let me know), and 2) a vasodialator you inject into the penis, like papaverine, phentolamine, or E Prostoglandin (Alprostadil), dunno if I spelled any of those names correctly.  So, I elected for 2) and the doc prescribed Edex, a form of Alprostadil, since papaverine is almost unavailable anymore.  We'll see how that works.

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