Showing posts with label viagra resistance. Show all posts
Showing posts with label viagra resistance. Show all posts

Monday, October 21, 2013

With Edex, I am a victim of my own success....

After our last wild (for us) night that I detailed in my previous post, which occurred on a Friday, I tried to tactfully suggest we go again on Sunday night, because the only thing about great sex is that it just makes you crave more of it!  But the wife's response was "Oh no, I would have to work up to that!" meaning she needed a rest before enduring THAT again....  I didn't know whether to be proud that I wore her out, or depressed that she found it so tiring to be intimate with me.  The thing about Edex is that it is so expensive (with my crappy health insurance, it costs $205 for 4 doses) along with he fact that when you have ED it just... feels... so... damn'...GOOD to be rock hard again that you want to take advantage of its effects while they last, both of which led to the amazing two-fer of that Friday.  

The aftermath of that night led to another short dry spell of two weeks, although on that second Friday when we usually get busy, we were lying in bed when The Little Woman began playing with my equipment and brought it to Chubby Status, which is about the best I can achieve without the help of chemistry.  She started diddling her fingers along the underside of my shaft, and bore in on that sensitive part about two inches down from the head, and she did it so intensely that I soon exploded all over myself.  She chuckled, apparently taking a kind of weird (to me) satisfaction in the copious result of her handiwork.  I was much appreciative and we were both tired, so we went to sleep without doing the do.  Then again on the next Monday she tried the same thing again, but then began some oral techniques which put me into orbit, although again she switched to manual mode at the last so she could observe the results.  I was again amazed and delighted, but I was beginning to get the impression that by doing these things she was attempting to keep The Monster at bay, and to be honest, she was succeeding, really!

Then it came to be Friday again, and after a sumptuous meal and quite a bit of wine, She said rather unceremoniously "Let's go to bed, and bring your stuff."  Wow!  With trembling hands I hurriedly readied the dose and injected it.  As I've said before, Edex takes a while to work, but it seemed that as we fooled around I was throbbing with anticipation in no time, but ever the dutiful lover, I kept on with the preliminaries until suddenly she pushed me onto my back and mounted me.  She rode me furiously for less than a minute before she did her little "Unngh!" thing, which is usually my cue to let go, but it had been so long and I was so IN THE ZONE, that stable plateau period where it feels so good you don't want it to end, that I couldn't seem to get out of it.  Now, my sexual performance has varied widely since even back before ED was a problem for me, but I've noticed and read about how it sometimes becomes more difficult to climax as you get older.  That, however, did not seem to be the problem this time:  it was just so...damn'... GOOD that I didn't want to stop, and eventually She began to get tired.  I offered to assume top position, but she acted as if she didn't hear me, actually getting kind of angry, chanting "Come on!" as she thrust back and forth.  She finally seemed to make a supreme "I'll show YOU!" effort, and thrusted so hard and so rapidly it drove me off the plateau and into the abyss.  Orgasms in real life seldom approach earth-shaking for me, but by golly this one had me shaking for what seemed like an outrageous amount of time.  I was spent!

Always the passive-aggressive one, she said "I'm sorry I didn't excite you enough to come right away..."  to which I replied "ARE YOU KIDDING ME???" along with some superlatives about her beauty and her performance, all of which were true, mind you.  That honest adoration on my part seemed to take the edge off her, somewhat, and when she lifted off me and I was drenched by a deluge of our combined juices, she again let out that weird little chuckle of satisfaction and it seemed that all was right with the World.  We cleaned up (it took me a LOT longer than it did her) and then came back to bed, but when I got there she was already fast asleep.  Looking at her lying there brought my Little Big Man almost all the way back to attention, but after playing around with it a bit I found that I was too tired to make the effort to work it through to completion. I was hit by a thunderbolt of amazement that I, too, would have to "work up to doing that again"!  Sheesh!

Wednesday, June 5, 2013

Where is my Stendra? And where is my ED 1000?

These are two ED treatments you've probably heard about if, like me, you research ED cures every other day hoping for a miracle.  Just in case you ain't heard, the miracle may be here, or rather, may be in Canada, Europe, and everywhere else except the USA!  The ED 1000 is a version of the ultrasonic shock wave machine that has been used successfully to grow new blood vessels in damaged heart muscle, now adapted for use on the penis to cure, that's right, CURE most ED problems.  It's made in the US and has been in use in Canada and the UK for a couple of years, and they report something like a 95% success rate.  The UK has pressed ahead with it because their National Health Service currently pays at least part of their citizens' Viagra and Cialis bills, so a cure would reduce that cost.  I read somewhere that the treatment takes 6 weeks and costs around $2100.  Hell, I'll spend almost that on EDEX this year alone!

Stendra is yet another PDE-5 inhibitor medication that supposedly was approved by the FDA in April, 2012, but I can't find any information on its availabilty.  My drugstore did not have it in its catalog, and I signed up for a newsletter on the manufacturer's website but have heard nothing from them.  Supposedly it works faster than Viagra, in like 15 minutes, and it wears off in an hour.  I thought I might try it, since every ED drug I've had works great for awhile then quits, except for Papaverine and EDEX which never fail.  We'll see....

UPDATE:  I read where the developer of Stendra finally obtained permission from the FDA to advertise that it was more fast-acting, and that having this permission persuaded another drug company to partner with the original developer in production and investment, etc.  Supposedly that means that Stendra may become available by the end of 2013.  Keeping my fingers crossed!  I've called a couple of ED clinics in Canada, but I've yet to find one that offers the ED 1000 treatment.

UPDATE, 03/13/2014: Stendra is now available.  There are numerous brochures sitting around in my urologist's offce advertising it, now.  Ya.  Hoo.

UPDATE, 05/05/2014:  I finally got my family doc to prescribe me Stendra.  The literature says that because I take Diltiazem for blood pressure, I should not take more than the lowest (50mg) dose, but that dose is on back-order everywhere for some reason, so he gave me some 100mg samples and said to cut 'em in half.  The first time I tried that, the other half of the pill went shooting out of sight and I never did find it.  The 50mg dose had absolutely no effect on my severe ED, so a day or so later I did a whole 100mg, which helped things but did not make it hard enough for penetration (although my angel of a wife cheerfully pleasured me orally!), so a couple days after that I did two 100mg tablets (they make a 200mg pill, so that's not outrageous) and it worked very well with no untoward effects, although it took a full 30 minutes to reach full power.  Still, supposedly you can take it with food, so that's a good thing!

UPDATE, 04/02/2015:  I'm on an ED1000 email list (subscribe at www.medispec.com) that says they are partnering with menshealthsolutions.ca in Canada to provide ED1000 treatment clinics.  The price for the treatment as of this date is $4000, although I dunno if that's USD or Loonies.  The on-line brochure also says ED1000 is approved as a treatment for Peyronie's, which is a surprise.  Not sure if I want to invest that much now and travel up North, or just wait until the treatment is approved in the US and might be covered at least partially by insurance.  Medispec's website has said for months that the ED1000 is in the final stage of clinical trials for approval by the FDA, so I wonder what the hold-up is, beyond maybe Pfizer, Lilly, the other PDE5 drug manufacturers trying to keep it off the market.  Oh, well....

Tuesday, April 23, 2013

Back to the Future: Edex Rules!

Since the PDE5 inhibitors aren't working for me anymore (see previous post), the doc prescribed a trial dosage of Edex, a brand of E Prostaglandin (Alprostadil) which you inject directly into the penis.  It's not as bad as it sounds, really!  Edex comes in little kits, with the drug prepackaged in solution in 10 microgram (or 20 mcg) cartridges.  You attach one of the included 29-gauge needles to the injector device which is like the outside of a syringe, insert the cartridge and then jab in the needle and push the device plunger down to inject the stuff.  This is a lot more convenient than it was with papaverine in the old days, where I would have to make up my own dosages/syringes, but it's also much more expensive.  The doc said to use 5 micrograms to start out, which you dose by squirting out the extra 5 mcg from the 10 mcg cartridge then inject all the rest.  If that didn't work, I was supposed to use a 10 mcg dose the next time. Well, you know I didn't want any failures the first time, so I thought I would inject 5 mcg and if nothing happened, I would inject the rest of the 10 mcg cartridge to buck up things and not waste anything.  The Little Woman and I had been drinking a little, too, so that may have clouded my judgement a little bit....

The problem was that even with my glasses I couldn't read the markings on the cartridge when I was holding it "down there", so I wound up just guessing by pushing the plunger part of the way down and then withdrew the needle.  It turned out I'd actually injected about 7 mcg worth, and even though they tell you it takes between 5 and 20 minutes to work, I got impatient when I didn't feel anything right away, so I stuck it in again and injected the rest of the cartridge.  Well!  Things started to happen then, lemme tell ya!  As soon as we started fooling around, Little Willie grew as big and hard as he's ever been, and actually started to ache a little bit (which is a common side effect, and it wasn't enough to make me stop going for the gusto).  She likes it on top so she can manipulate things to maximize her pleasure (and who am I to complain?), and very early on she became Cowgirl UP!  She even threw up her hand like she was riding a bronco, there for a bit.  She pounded me back and forth inside her so hard I was afraid I might get hurt....  She came first, but gamely rode me until I exploded.  She lay on top of me for a few minutes, then noticed I was still somewhat hard, and son of a gun, she mounted up and rode me to town again!  ....The third time, I told her she didn't have to do that, that the dose of Edex I'd taken would probably not let it go down for awhile, but she went at it again anyway (you can see why I love this woman), and danged if she didn't force out another climax from me, albeit much smaller than the first two.  I was spent, literally, and she was tired.  We both drifted off to sleep, but after an hour I woke up and was still hard.... I began to get alarmed, fearing that a trip to the hospital was going to be necessary.

In the old days my now ex-wife would never want to go around a second time, EVER, so I often found that the climax produced by a bout of self-love would trigger enough relaxation that the erection would subside faster.  This time, however, nothing doing.  When I reached the 3 hour mark things had softened only a little bit, but I was tired and set my alarm for 1.5 hours later, resolving to go to the emergency room if by then nothing had changed.  Just before the alarm went off I woke up again, and to my relief Wille was Little again.  Whew!  The next time I'm sticking to the 5 mcg dose, I swear!

PS:  I thought the, um, artificiality of things might be off-putting to my wife, but the next morning the Little Woman was affectionately calling me Iron Man, an apt analogy, really. She really didn't seem to care why it worked, was just happy it did.  Let me tell you, though, things are not totally artificial-- if there is no arousal on my part, the inside hardness will be there but the head remains small and the outside skin is a little loose.  Get me excited, though (as she almost always does with ease), and everything expands correspondingly, and then some, so it ain't all just the drugs, man.  EDEX RULES!!!

Tuesday, April 16, 2013

Viagra Resistance/Viagra Tolerance: It's a Real Thing!

As I said in an earlier post, the wonder drug Cialis quit working for me a couple of years ago, so I went back on Viagra (the 100 mg tablet, this time), and it worked GREAT, although it didn't give you that 36 hours of readiness that Cialis did.  Well, now the effectiveness of my beloved blue diamonds has begun to decrease, so that I can no longer achieve a strong enough erection for sex even though Little Willie does get somewhat expanded.  The urologist suggested a penis ring, but that only helped a little bit.  If you google "Viagra resistance" you'll find an herbal remedy sales website that cites an issue of the International Journal of  Impotence Research which details a study that suggests the efficacy of Viagra and other PDE5 inhibitors decreases over time, requiring stronger doses.  I'm here to tell ya, though, that after awhile even higher doses don't work. I wasn't able to find the actual IPIR article....But I went so far as to take two 100mg Viagras at once, with not much real effect. So, my only other options are 1) a penis pump/penis ring combo, which sounds like a lot of work for dubious reward if you ask me (if you have one of those things and are happy with it, just let me know), and 2) a vasodialator you inject into the penis, like papaverine, phentolamine, or E Prostoglandin (Alprostadil), dunno if I spelled any of those names correctly.  So, I elected for 2) and the doc prescribed Edex, a form of Alprostadil, since papaverine is almost unavailable anymore.  We'll see how that works.